Endocrine Abstracts

Objective: The metabolic syndrome (MetS) is a cluster of metabolic abnormalities with insulin resistance (IR) as a major characteristic. It has been recently questioned that MetS and its related components are associated with functional and morphological alterations of thyroid gland. Aim of our study is to examine thyroid volume and nodule prevalence in patients with MetS in a mild-to-moderate iodine deficient area.Design: Two hundred and seventy-eight p...

Objective: Efficacy of eutectic mixture of local anesthetics (EMLA) cream and the needle-free injection of local anesthesia for reducing the pain associated with fine-needle aspiration biopsy (FNAB) of thyroid nodules was previously reported. However, direct comparison of the analgesic efficacy for both methods has not been established yet. The aim of this study was to compare the analgesic efficacy of EMLA cream and needle-free injection of lidocaine for FNAB-associated pain....

Objective: Morphologic and functional platelet abnormalities have been previously reported in patients with type 2 diabetes mellitus (DM) and some of these abnormalities have been linked to increased cardiovascular risk. Mean platelet volume (MPV) informs not only about platelet size, but also about its functions. Larger platelets bear more thrombotic potential. Higher MPV values have been correlated with cardiovascular events in the short and long run. Previous studies have d...

In this study we compared plasma adiponectin levels between patients with non-functional adrenal incidentaloma and subclinical Cushing’s syndrome. Our aims were to determine whether there was any difference of plasma adiponectin levels, any relation between cardiovasculer risk factors and to investigate the importance of adiponectin levels in subclinical Cushing’s syndrome patients according to non-functional adrenal incidentaloma patients. The patients referred from...

Distant metastases as initial manifestation of follicular thyroid carcinoma is rare. We report a case of an unusual initial presentation of follicular thyroid carcinoma on follow-up. A 52-year-old woman presented with a 12-month history of progressively enlarging mass in the anterior chest wall. The mass was fixed to the chest wall, measuring 12×10 cm in diameter. Computed tomography demonstrated a lobulated soft-tissue mass (17×11×6 cm) destructing sternum and ...

To asses the presence of antibodies to BIP/GRP78, which is a chaperon of endoplasmic reticulum and has immune modulating and antiapoptotic effects in Hashimoto’s thyroiditis.The study included 62 patients with autoimmune thyroiditis. Of these, 20 had euthyroid, 27 had subclinical hypothyroid, and 15 had hypothyroid Hashimato’s thyroiditis. A control group including 37 healthy patients also participated in the study.There ...

Primary hyperparathyroidism in the most common cause of hypercalcemia. 87% of the cases present with single adenoma, 9% of them have hyperplasia, while multiple adenomas and parathyroid malignancy are detected in 3 and 1% of the cases, respectively. Although it is rare, parathyroid adenomas may be ectopic. The most common locations for ectopic parathyroid adenomas are thymus, tracheaesophageal cleft, carotis sheet, intrathyroidal and paraesophageal area. In this study, we aime...

Acromegaly affects 4–6 people in a million and hypophyseal GH releasing adenoma is the most common cause of the disease. It shows its effects on GH and IGF1. Since they grow rapidly, they are usually diagnosed at the stage of macroadenomas. Heart failure, arthritis, OSAS and DM may develop during course of the disease. Although the most common accompanying malignancy is colon cancer, the incidence of malign melanoma, breast, thyroid, gastric and lung cancers is also incre...

Aim: There are some studies suggesting that the risk of developing cancers,especially thyroid cancer, is increased in the patients with acromegaly. The prevalence of thyroid cancer is 1.2-10.6% among the patients with acromegaly. In this study, we aimed to evaluate clinical and histopathologic characteristics of thyroid cancer among the patients with acromegaly.Method: We retrospectively evaluated the patients with acromegaly who had been followed-up by ...

Hyalinizing trabecular tumor is an uncommon, controversial lesion of thyroid gland. Hyalinizing trabecular neoplasm share similarities with medullary thyroid carcinomas (MTC) and exhibit nuclear features resembling papillary thyroid carcinoma (PTC). However, the clinical behaviour unclear. We aimed to present a rare case of hyalinizing trabecular tumor of thyroid gland and ten-year follow up. A 54-year-old woman who was being followed up because of multinodular goiter on exami...